姓名:翁玥
职称职务:博士,副教授,湖北省“楚天学子”,“湖北省百人”创新人才,硕士生导师
邮箱:wengyue@hubu.edu.cn
研究兴趣与专长
(1)生物偶联化学、生物正交化学及生物功能分子的修饰
(2) 有机合成方法学
(3) 金属有机化学机理研究
教育与研究经历
2020 –至今
8858cc永利官网,8858cc永利唯一官方网,副教授
2017 – 2020
博士后,台湾同步辐射研究中心,中国台湾,导师:苏群仁 研究员
2016 – 2017
博士后,Leibniz催化研究所,德国,导师:Matthias Beller教授
2014 – 2016
博士后,剑桥大学化学系,英国,导师:Matthew Gaunt 教授
2013 – 2014
博士后,牛津大学化学系,英国,导师:Benjamin Davis 教授
2006 – 2012
武汉大学化学与分子科学学院,博士,导师:雷爱文教授
2007 – 2009
Scripps研究所,美国,国家建设高水平大学公派研究生项目联合培养博士,
导师:张庆海教授
2005 – 2006
香港浸会大学,联合培养学士,导师:Ricky Wong教授 / Winghong Chan教授
2002 – 2006
武汉大学化学与分子科学学院,学士
主要研究成果
(1) Y. Weng, B. Ding, Y. Liu, C. Song, L.-Y. Chan, and C.-W. Chiang*, “Late-Stage Photoredox C-H Amidation of N-Unprotected Indole Derivatives: Access to N-(Indol-2-yl)amides” Org. Lett. 2021, 23, 2710-2714.
(2) Y. Weng, C. Song, C.-W. Chiang,* and A. Lei*, “SET-based Peptide/protein Bioconjugations Driven by Biocompatible Energy Input ”, Commun. Chem. 2020,3,171.
(3) Y. Weng, B. Cheng, C. He, A. Lei,* “Rational Design of a Pd-Catalyzed Csp–Csp Cross- Coupling Reaction Inspired by Kinetic Studies”, Angew. Chem., Int. Ed. 2012, 51, 9547-9551.
(4) C. Song, K. Liu, X. Jiang, X. Dong, Y. Weng,* C.-W. Chiang,* and A. Lei*, “Electrooxidation enables selective dehydrogenative [4+2] annulation between indole derivatives”, Angew. Chem. Int. Ed. 2020, 59, 7193-7197.
(5) B. Ding, Y. Weng,* Y. Liu, C. Song, L. Yin, J. Yuan, Y. Ren, A. Lei*, and C.-W. Chiang*, “Selective Photoredox Trifluoromethylation of Tryptophancontaining Peptides”, Eur. J. Org. Chem., 2019, 46, 7596-7605.
(6) C. Song, K. Liu, Z. Wang, B. Ding, S. Wang, Y. Weng,* C.-W. Chiang,* and A. Lei,* “Electrochemical Oxidation Induced Selective Tyrosine Bioconjugation for the Modification of Biomolecules”, Chem. Sci., 2019, 10, 7982-7987.
(7) 江建纬, 翁玥, 张和, 雷爱文,“一种可见光诱导吡唑偶联苯丙氨酸类化合物的方法”专利号:201810091709.5 (2018)
(8) S. G. Aller, J. Yu, A. Ward, Y. Weng, S. Chittaboina, R. Zhuo, P. M. Harrell, Y. T. Trinh, Q. Zhang, I. L. Urbatsch, G. Chang*, “Structure of P-Glycoprotein Reveals a Molecular Basis for Poly-Specific Drug Binding”, Science 2009, 323, 1718-1722.